sertraline-related bleeding tendency: could it be dose-dependent?

Sertraline-Related Bleeding Tendency: Could It Be Dose-Dependent?

Selective serotonin reuptake inhibitors (SSRIs) are reported to be associated with increased bleeding tendency. While findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue SSRIs as harmful medications. We report two instances of dose-dependent relations between sertraline and bleeding tendency. Bleeding diathesis was a...

Sertraline-related Bleeding Tendency: Could it be Dose-dependent?

Selective serotonin reuptake inhibitors (SSRIs) are reported to be associated with increased bleeding tendency. While findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue SSRIs as harmful medications. We report two instances of dose-dependent relations between sertraline and bleeding tendency. Bleeding diathesis was a...

Primary Idiopathic Osteoarthropathy: Could It Be Related to Alcoholism?

Background. Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by abnormal proliferation of the skin and bony structures at the distal extremities resulting in digital clubbing, periosteal bony reaction, and joint effusion. It can be primary (idiopathic) without any clear identifiable etiology as well as secondary to variety of systemic diseases most notably lung pathology. Case Pr...

Could it be Lyme neuroborreliosis?

Recurrent Vulvovaginal Candidiasis: Could It Be Related to Cell-Mediated Immunity Defect in Response to Candida Antigen?

Objective Recurrent vulvovaginal candidiasis (RVVC) is a common cause of morbidity affecting millions of women worldwide. Patients with RVVC are thought to have an underlying immunologic defect. This study has been established to evaluate cell mediated immunity defect in response to candida antigen in RVVC cases. MaterialsAndMethods Our cross sectional study was performed in 3 groups of RVVC pa...

Bleeding tendency in uremia.

LTHOIJGH the association of bleeding teuideuicy with uremia has beeui recognized fon’ at least a century,n the exact (‘ause has miever 1)een clearly defined. Vascular damage has been suggested.2 This study includes assays of many hemostatic factors in twelve patients showing varying degrees of azotelllia with and without hemorrhagic manifestations. An abnormality in platelet function (thrombocy...